Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future? Symptoms that increase with age, such as cardiovascular disease,…
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Novel protein could reverse severe muscle wasting in disease, aging and trauma
When we tear a muscle ” stem cells within it repair the problem. We can see this occurring not only in severe muscle wasting diseases such as muscular dystrophy and in war veterans who survive catastrophic limb injuries, but also…
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Beyond secretion of insulin, the novel function of beta cells in regulating glucose homeostasis
In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s group and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of…
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A novel drug target for neonatal and infant heart failure
Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment. Approximately 60 percent of children born with congenital heart abnormalities will develop overt heart failure within…
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Cornea appears to resist infection from novel coronavirus
New findings from researchers at Washington University School of Medicine in St. Louis suggest the eye’s cornea can resist infection from the novel coronavirus. Although the herpes simplex virus can infect the cornea and spread to other parts of the…
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A novel monoclonal antibody therapy cuts LDL cholesterol by half in a high-risk patient population
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and…
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Could the novel coronavirus become a seasonal virus? New study suggests yes — but not yet
Coronavirus and seasonal allergies: How to spot the difference As kids begin to head back to school, the Centers for Disease Control and Prevention (CDC) has provided some guidelines for parents to help them distinguish between seasonal allergies and COVID-19,…
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Novel immune-oncology approach for potential cancer treatment
A research collaboration between Monash University and Lava Therapeutics details a novel immune-oncology approach for the potential treatment of cancer. Instrumental to the study was co-first author Dr. Roeland Lameris from Amsterdam UMC and colleagues from the University of Melbourne….
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Novel label-free imaging technique brings out the inner light within T cells
T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells…
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Novel therapeutic approaches for aggressive bone cancer
Osteosarcoma (OS) is the most common form of aggressive bone cancer. A MedUni Vienna study led by geneticist Erwin Wagner has uncovered new insights into the disease mechanisms of OS, paving the way for potential new diagnostic and treatment strategies…
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