Impaired intelligence, movement disorders and developmental delays are typical for a group of rare diseases that belong to GPI anchor deficiencies. Researchers from the University of Bonn and the Max Planck Institute for Molecular Genetics used genetic engineering methods to…
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COVID-19 unmasked: Math model suggests optimal treatment strategies
Getting control of COVID-19 will take more than widespread vaccination; it will also require better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as…
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Getting it just right: The Goldilocks model of cancer
Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a…
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COVID-19 model inspired by gas-phase chemistry predicts disease spread
A COVID-19 transmission model inspired by gas-phase chemistry is helping the Centers for Disease Control and Prevention (CDC) forecast COVID-19 deaths across the country. Developed by Yunfeng Shi, an associate professor of materials science and engineering at Rensselaer Polytechnic Institute,…
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Researchers test a comprehensive model intervention to reduce opioid overdose deaths in hard-hit communities
National Institutes of Health and other federal leaders outlined their vision for a groundbreaking study that will aim to address gaps in reaching communities most heavily affected by the opioid epidemic with proven, evidence-based interventions for opioid use disorder (OUD)….
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New 3-D model of a DNA-regulating complex in human cells provides cancer clues
Scientists have created an unprecedented 3-dimensional structural model of a key molecular “machine” known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and some other diseases. The researchers, led by Cigall Kadoch, Ph.D., of…
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Model says COVID-19 deaths could surpass 317,000 by December
(HealthDay)—A widely cited model for COVID-19 deaths in the United States predicts a total of 317,000 deaths by December. On Friday morning, a model from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington forecasts that…
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Researchers develop model to predict likelihood of testing positive for COVID-19, disease outcomes
Cleveland Clinic researchers have developed the world’s first risk prediction model for healthcare providers to forecast an individual patient’s likelihood of testing positive for COVID-19 as well as their outcomes from the disease. According a new study published in Chest,…
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Researchers use ALCF resources to model the spread of COVID-19
With COVID-19 drastically altering daily life for people across the planet, the U.S. Department of Energy’s (DOE) Argonne National Laboratory has moved quickly to join the global fight against the pandemic. Among the laboratory’s most powerful resources for scientific research…
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Model predicts economic, public health repercussions of lifting quarantine before COVID-19 vaccine
COVID-19, the disease caused by the SARS-Cov-2 virus, was officially declared a pandemic on March 11 by the World Health Organization. Nearly two months later, many municipalities and states around the country have decided to relax some of the limitations…
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