Take a nice, deep breath. Now imagine your lungs: Myriad airways like branches, each with tiny alveoli-like leaves. This alveolar structure is key to the absorption of oxygen and excretion of carbon dioxide that we call “breath.” As we breathe,…
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Machine-learning model can detect rare cardiomyopathy
A machine-learning model can identify patients at risk of a rare cardiomyopathy, according to a study published in Nature Communications. Transthyretin amyloid cardiomyopathy (ATTR-CM) can cause heart failure and should be treated differently than other causes of heart failure, so…
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New mouse model for studying the cognitive protection mechanisms in Alzheimer’s
Alzheimer’s is a neurodegenerative disease that features the accumulation of the beta-amyloid peptide and Tau protein in the brain, which are associated with deficits in the neuronal connections and with dementia. However, researchers have recently discovered a type of people…
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Dynamic heart model mimics hemodynamic loads, advances engineered heart tissue technology
Efforts to understand cardiac disease progression and develop therapeutic tissues that can repair the human heart are just a few areas of focus for the Feinberg research group at Carnegie Mellon University. The group’s latest dynamic model, created in partnership…
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Can a Subscription Model Fix Primary Care in the US?
In April, San Francisco-based primary care company One Medical revealed an eye-popping compensation package for its chief executive and chairman, Amir Dan Rubin. His $199 million payday, particularly noteworthy at a company that has yet to turn a profit, made…
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A new mouse model gave surprising findings about Folling Disease
In Norway, all newborn children are tested for 25 rare genetic diseases through the Newborn Screening program, and the most common of these is phenylketonuria (abbreviated to PKU), known as Folling Disease. Every year, between 3-7 children are born in…
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FDA-approved antidiarrhea drug can reverse resistance to chemotherapy in a mouse model of leukemia
New research into one of the most common and difficult cancers to treat has revealed an effective route to mitigating chemotherapy resistance through the use of a drug already approved by the FDA to treat diarrhea. The findings are published…
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Model identifies risk of serious complications following surgery
Heart attack, kidney failure, stroke. These are just a few of the life-threatening complications that patients are at risk for following surgery. Now Jefferson researchers have developed an easy-to-use, web-based tool that predicts the risk of post-surgical complications such as…
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He Wanted to Be a Healthier Role Model for His Kids, So He Ran Off 190 Pounds
Name: Daniel HertelAge: 28Hometown: Buffalo Start Weight: 378 poundsEnd Weight: 188 poundsTime Running: 10 months Before I went on my weight-loss journey, I weighed nearly 400 pounds. Because of this, I was always out of breath and tired—not to mention…
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Study identifies a nonhuman primate model that mimics severe COVID-19 similar to humans
Aged, wild-caught African green monkeys exposed to the SARS-CoV-2 virus developed acute respiratory distress syndrome (ARDS) with clinical symptoms similar to those observed in the most serious human cases of COVID-19, report researchers in The American Journal of Pathology, published…
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