Skip to: The Process Application of SATI in a Mouse-model Progeria Study The Future of Gene Editing? One strategy for studying and understanding biological processes and inherited conditions is gene splicing. The technology lies at the cutting-edge of research into…
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DNA discovery could advance degenerative disease treatments
New research on the structure and dynamics of a branched form of DNA called a three-way junction could lead to more effectively targeted treatments for degenerative disorders like Huntington’s Disease, scientists say. In a new paper published in the journal…
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A subtle change in DNA may predispose to polyneuropathy after gut infection
Guillain-Barré syndrome is an infamous autoimmune neuropathy, yet genetic variants predisposing individuals to this disease have yet to be described. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered two novel genetic variants in a protein…
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Editing the DNA of human embryos could protect us from future pandemics
Hollywood blockbusters such as X-men, Gattaca and Jurassic World have explored the intriguing concept of “germline genome editing”—a biomolecular technique that can alter the DNA of sperm, eggs or embryos. If you remove a gene that causes a certain disease…
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Wistar creates a new synthetic DNA vaccine against Powassan virus
Scientists at The Wistar Institute have designed and tested the first-of-its-kind synthetic DNA vaccine against Powassan virus (POWV), targeting portions of the virus envelope protein. A rapidly reemerging tick-borne disease, POWV has been reported to be fatal in 10% of…
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Cell-free DNA provides a dynamic window into health
Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers can identify the tissue from which the…
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Light-activated ‘CRISPR’ triggers precision gene editing and super-fast DNA repair
In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and…
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Study into DNA biology could impact future anti-cancer therapies
A study by the Centre for Chromosome Biology at NUI Galway, Ireland, in partnership with the University of Zurich, has uncovered new insights into how the replication of DNA occurs which can be applied to help develop novel cancer treatments….
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