The journal Oncotarget has published “Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication” which reported that the serine/threonine kinase Pim-1 is upregulated downstream of…
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How to protect your DNA data
Knowing how to protect your DNA data is incredibly important, because your genetic code is the blueprint for much of who you are. Thanks to the development of cheap genomics, at-home DNA testing kits from Ancestry, 23andMe, MyHeritage and others…
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Strange DNA ‘borgs discovered in California
Scientists accidentally discovered a mysterious — and unusually large — DNA structure deep in the mud in California wetlands. The structure, known as a “Borg,” likely belongs to a single-celled organism and carries many genes that are unknown to science….
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New DNA research could help combat cancers resistant to current treatments
In a groundbreaking first, research led by Queen’s University Belfast has found thousands of “Achilles Heels’ or ‘cancer vulnerabilities’ in an analysis of more than 700 different cancer cell types. In the future, this could lead to new ways to…
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A new method for efficient and automated production of synthetic DNA
Chemically synthesized short DNA sequences are extremely important ingredients with countless uses in research laboratories, hospitals, and in industry, like in the method for identifying COVID-19. Phosphoramidites are necessary building blocks in the production of DNA sequences, but they are…
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Black swan DNA could offer insight into how humans respond to bird flu
In a world-first, scientists from The University of Western Australia have assembled the entire DNA of the black swan, which could offer insight into how the bird, and even humans, respond to bird flu and other pandemics in the same…
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HP1a is a key epigenetic regulator that maintains chromosome integrity
The information of the human genome is encoded by approximately 3 billion DNA base pairs and packaged into 23 pairs of chromosomes. If all chromosomes could be disentangled and linearly aligned, they would be a thin thread of about 2…
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New machine learning method for designing more effective antibody drugs
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies are extremely…
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Altering a mosquito's gut genes shows promise to curb malaria
Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife. The study is the latest in…
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Mutations in overlooked DNA could have profound impact on survival for bowel cancer patients
Mutations in the DNA of the cell’s energy ‘factories’ increases the chances of survival for people with bowel cancer, according to a study published today in Nature Metabolism. Scientists funded by Cancer Research UK have found that patients with colorectal…
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