In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases (CRID), linked to the University of São Paulo (USP) in Brazil, discovered a novel path in…
Read More
Study reveals unknown immune defense system that protects the lungs from viral infections
Researchers have uncovered a previously unknown arm of the immune defense system that protects the lung from lethal viral infections. Respiratory diseases caused by viruses such as influenza A and SARS-CoV-2 cause damage not just through their own actions, but…
Read More
New method for growing embryos outside the womb
To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought grail…
Read More
The bald truth—altered cell divisions cause hair thinning
Hair grows from stem cells residing in hair follicles. During aging, the capability of hair follicles to grow hair is successively lost, leading to hair thinning and ultimately hair loss. In a new study, researchers from Tokyo Medical and Dental…
Read More
Impact of type I interferon (IFN) autoantibodies in critical COVID-19
The emergence and rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered the coronavirus disease 2019 (COVID-19) pandemic. To date, over 118 million cases have been confirmed, and over 2.6 million have lost their lives. The sheer…
Read More
Study reveals how lung alveolus forms at cellular level
Researchers from Children's Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better sense of how to develop therapies and…
Read More
Researchers shed light on T-cell receptor activation in response to infection
Immune cells specialize to ensure the most efficient defense against viruses and other pathogens. Researchers at the University of Basel have shed light on this specialization of T cells and shown that it occurs differently in the context of an…
Read More
Detecting hidden circulating tumor cells in non-small cell lung cancer patients
Non-Small Cell Lung Cancer (NSCLC) is the most prevalent form of lung cancer, accounting for more than 80 percent of all lung cancer cases. Despite the aggressive nature of NSCLC, circulating tumor cells that lead to metastases often go undetected…
Read More
New inhibitor makes drug-resistant tumor cells respond again to chemotherapy
A new substance could improve the treatment of persistent cancers. Researchers at Martin Luther University Halle-Wittenberg (MLU) and the University of Greifswald have developed a new inhibitor that makes drug-resistant tumor cells respond again to chemotherapy. The new substance blocks…
Read More
Novel host-viral-microbiome interactions during COVID-19 may determine outcome
The current pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been spreading rapidly for over a year. Though primarily a respiratory illness, its manifestations are often protean and may be life-threatening….
Read More