Decreasing DNA repair and genomic instability

Decreasing DNA repair and genomic instability

The journal Oncotarget has published “Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication” which reported that the serine/threonine kinase Pim-1 is upregulated downstream of…

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