Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease. Understanding the genetic variations associated with the disease represents an important step for drug development. Now,…
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Scientists unlock promising key to preventing cancer relapse after immunotherapy
Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed…
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New dopamine sensors could help unlock the mysteries of brain chemistry
In 2018, Lin Tian and her team at UC Davis Health developed dLight1, a single fluorescent protein-based biosensor. This family of highly specific sensors detects dopamine, a hormone released by neurons to send signals to other nerve cells. When combined…
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Unlock 1.0: Expert tips for you to detox right
Over the past few months, we have all experienced moments that are more reminiscent of sci-fi novels than real life: all about competing on social media and house parties held via a computer screen. Perched in front of the laptop…
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Researchers unlock TB vaccine puzzle in findings that could save millions of newborns
An international research team has identified the mechanism behind one of science’s most enduring mysteries: what makes the 100-year-old tuberculosis (TB) vaccine so effective at preventing newborn deaths from diseases other than TB? The ability of Bacillus Calmette-Guérin (BCG)—one of…
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