A protein in tumor cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown. The scientists, from the Wellcome Sanger Institute, University of Cambridge and Harvard University, have identified…
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TikTok-Approved Dash Has Another Appliance That Will Change Your Breakfast Game
Ever since we discovered the Dash mini waffle maker on TikTok, we’ve become mega fans of all things from the popular brand. From a mini rice cooker to snow cone machines, Dash has just about every appliance we could ask…
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The One Thing Target Employees Want You To Stop Doing
Let’s be real: Target is a wonderland of everything one could ever want, need, or dream of. It’s easy to get lost in any store, wandering up and down every single aisle (sometimes more than once) in order to find…
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New therapeutic target for Huntington’s treatment
Huntington’s disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein mHTT,…
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Common neural circuit and potential target for anxiety and obsessive-compulsive disorder
Anxiety disorders and obsessive-compulsive disorder (OCD) are disabling psychiatric conditions, and major contributors to the global burden of nonfatal illness. The lifetime prevalence of anxiety disorders in adults under 60 years ranged from approximately 30-35%, whereas the lifetime prevalence in…
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A novel drug target for neonatal and infant heart failure
Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment. Approximately 60 percent of children born with congenital heart abnormalities will develop overt heart failure within…
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Potential drug target revealed to help more children survive a lethal heart defect
When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before age 25. Now,…
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Drug target for aggressive breast cancer found
A team of British and American scientists have discovered a way to slow the growth of breast cancer stem cells in the lab. The study led by Dr. Bruno Simões and Professor Rob Clarke from The University of Manchester could…
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Researchers identify possible drug target for prostate cancer
Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases. Castration-resistant prostate cancer is a highly aggressive form of prostate cancer that often leads…
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A new strategy to trigger ferroptosis in target cancer cells using drug-metal coordination complexes
Rapidly increasing cancer incidence and mortality worldwide have raised great challenges for the currently available anticancer options, which warrants the development of new therapeutic modalities based on novel antitumor mechanisms. Ferroptosis, a recently discovered form of non-apoptotic cell death, is…
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