Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one…
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Resistance to certain cancer therapies may be caused by loss of anti-tumour protein : Study
According to Penn State College of Medicine researchers, the absence of a protein that works to prevent tumour formation may explain why some patients are resistant to common cancer therapy. They said that testing cancers for the presence of this…
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The protein helping to explain foot-and-mouth’s infectiousness
Scientists have conducted a ‘molecular dissection’ of a part of the virus that causes foot-and-mouth disease, to try and understand why the pathogen is so infectious. Foot-and-mouth disease is a highly contagious infection of cloven-hoofed animals which affects agricultural production…
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Scientists identify protein that protects against Lyme
Yale researchers have discovered a protein that helps protect hosts from infection with the tick-borne spirochete that causes Lyme Disease, a finding that may help diagnose and treat this infection, they report Nov. 11 in the journal PLOS Pathogens. Lyme…
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Study shows similar antibody response to key SARS-CoV-2 ‘spike’ protein in COVID-19
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that antibody responses to SARS-CoV-2 are similar in COVID-19 patients with and without diabetes, and thus are unlikely to be responsible for the…
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How the regulator is regulated: Insight into immune-related protein holds therapeutic value
In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs. This type of immune therapy is also used for cancer treatment, owing to the important role that immune cells play in cancer…
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Alzheimer-linked protein complex at super resolution
With the advent of super-resolution microscopy, scientists can study close protein associations better than ever before. In the latest edition of eLife, the team of Wim Annaert (VIB-KU Leuven) combines state-of-the-art imaging techniques to investigate the distribution of γ-secretase, a…
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Could allergic reactions be prevented? Team identifies key protein that triggers symptoms
Spring is in the air, and that means allergic reaction-causing pollen is, too. It’s reported that 20 percent of the Canadian population lives with hay fever and nearly 10 percent have food allergies. And the problem is only getting worse….
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Muscle protein abundant in the heart plays key role in blood clotting during heart attack
A prevalent heart protein known as cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot—worsening damage to heart tissue, a new study shows. A team led by…
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A protein that controls inflammation
A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, and psoriasis. They discovered how the protein…
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