Bottom Line: Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments….
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Antibiotics may be the new weapon to fight against melanoma
Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumors in mice. Their findings were published in the Journal of Experimental…
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Study describes differences between mutation profile of acral nevi and acral melanoma
Melanocytic nevi, or moles, are nonmalignant growths that arise from pigment producing cells of the skin. They are mostly found in sun-exposed areas; however, they also can be found in sun-protected areas, such as the palms, soles of feet and…
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Wrong Daughter Told She Lacks Melanoma Mutation, Then Gets It
Parents who filed a multiparty claim after their daughters’ genetic cancer test results were mistakenly mixed up will have their day in court, according to a report in the Detroit Free Press. In 1999, Michael and Susan Lonsway brought their…
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Scientists identify new biomarkers in patients with malignant melanoma, which could help in its diagnosis and prognosis
A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant…
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Modified CRISPR/Cas9 complex targets specific histones
Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle. Rice University researchers have achieved something of the sort with a new genome editing tool that targets the supporting players in a…
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Methoblastin PFS
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. METHOBLASTIN® PFS methotrexate (meth-o-TREX-ate) Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about METHOBLASTIN® PFS. It does not contain all the…
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Response to adjuvant bevacizumab among patients with resected melanoma may vary by age
Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not, according to results published in Clinical Cancer Research, a journal of the American Association for…
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New targets for melanoma treatment
A collaborative study led by Monash University’s Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute (ONJCRI) has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumors and could pave the way for therapeutic vaccines to…
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New nanosystem enhances treatment for melanoma in animal models
Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU’s Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the…
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