Scientists at St. Jude Children’s Research Hospital alongside global partners are studying a common TP53-R337H variant found among people of Brazilian descent. The researchers found that a variant in the tumor suppressor gene XAF1 increases cancer risk when combined with…
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Inherited mutation can predispose children to a type of brain tumor
Investigators at St. Jude Children’s Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric medulloblastoma. The work appears as an advance online…
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