In a long-term collaboration between researchers and industry, an exciting first step has been made in the creation of a new generation of medicines for auto-immune diseases using one of our body’s own anti-inflammatory off-switch molecules. The immune system produces…
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Understanding the inflammation that causes death in COVID-19 patients
As clinical evidence mounts that the leading cause of death in COVID-19 patients is the dangerous condition known as a cytokine storm, University of Alberta researchers have identified a protein in the blood that could be responsible. The team found…
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Researchers use ultrasound to reduce COVID-19-related inflammation
Researchers at University of California San Diego School of Medicine have begun a pilot clinical trial to test the efficacy of using ultrasound to stimulate the spleen and reduce COVID-19-related inflammation, decreasing the length of hospital stays. "It's a pilot…
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Corticosteroids not recommended to treat smell loss due to Covid-19, study shows
Steroids should not be used to treat smell loss caused by Covid-19 according to an international group of smell experts, including Prof Carl Philpott from the University of East Anglia. Image Credit: University of East Anglia Smell loss is a…
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Defects in specific goblet cells may be a factor contributing to ulcerative colitis
There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg. The study indicates that defects in goblet cells of a particular type may…
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Novel diabetes subgroups show differences in biomarkers of inflammation
Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future? Symptoms that increase with age, such as cardiovascular disease,…
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Experimental evidence that ADAM17 inhibition prevents severe COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus that is contagious in humans. It is the causal agent of the ongoing coronavirus 2019 (COVID-19) pandemic. This virus causes a mild to severe infection and has…
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Exercise could be used to improve the oral environment in people with NAFLD
Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut. Bacteria that cause inflammation in the mouth are transported through the digestive tract to the gut…
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Experimental antibodies for Parkinson’s, Alzheimer’s may cause harmful inflammation
A team led by scientists at Scripps Research has made a discovery suggesting that experimental antibody therapies for Parkinson’s and Alzheimer’s have an unintended adverse effect—brain inflammation—that may have to be countered if these treatments are to work as intended….
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Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis
In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases (CRID), linked to the University of São Paulo (USP) in Brazil, discovered a novel path in…
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