Whether it's plankton exposed to parasites or people exposed to pathogens, a host's initial immune response plays an integral role in determining whether infection occurs and to what degree it spreads within a population, new University of Colorado Boulder research…
Read More
New machine learning method for designing more effective antibody drugs
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies are extremely…
Read More
Researchers identify SARS-CoV-2 antiviral compounds using protein assay
On March 11, 2020, the World Health Organization (WHO) announced the coronavirus disease 2019 (COVID-19) to be a pandemic. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, which is deemed to be highly contagious…
Read More
Researchers discover a new monoclonal antibody that is effective against SARS-CoV-2 variants
A new monoclonal antibody targets a particular region of the receptor-binding domain (RBD) on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This region is usually not accessible to immune cells, which may be why it has broad neutralizing capabilities….
Read More
Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function
The onset of the coronavirus disease 2019 (COVID-19) brought about intensive research on the biological characteristics of the pathogen responsible, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The immune response mediated by neutralizing antibodies, elicited by the virus or…
Read More
Study reveals unknown immune defense system that protects the lungs from viral infections
Researchers have uncovered a previously unknown arm of the immune defense system that protects the lung from lethal viral infections. Respiratory diseases caused by viruses such as influenza A and SARS-CoV-2 cause damage not just through their own actions, but…
Read More
Researchers shed light on T-cell receptor activation in response to infection
Immune cells specialize to ensure the most efficient defense against viruses and other pathogens. Researchers at the University of Basel have shed light on this specialization of T cells and shown that it occurs differently in the context of an…
Read More
Novel host-viral-microbiome interactions during COVID-19 may determine outcome
The current pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been spreading rapidly for over a year. Though primarily a respiratory illness, its manifestations are often protean and may be life-threatening….
Read More
Studies reveal the promise of newly engineered bispecific antibodies against tumor cells
Three studies – one each in Science, Science Translational Medicine, and Science Immunology – reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases….
Read More
Coronavirus to SARS-CoV-2 infection, but not immunity? – Naturopathy Naturopathy Specialist Portal
Corona-infection: do Not automatically immune? According to the Federal centre for health education (BZgA), studies have shown that people develop after arrested by the SARS-CoV-2-infection-specific antibodies. “It is unclear, however, how robust and durable this immune status is established, and…
Read More