Skip to: The Process Application of SATI in a Mouse-model Progeria Study The Future of Gene Editing? One strategy for studying and understanding biological processes and inherited conditions is gene splicing. The technology lies at the cutting-edge of research into…
Read More
Rare genetic syndrome identified, caused by mutations in gene SATB1
Advances in DNA sequencing have uncovered a rare syndrome which is caused by variations in the gene SATB1. The study, co-authored by academics from Oxford Brookes University (UK), University of Lausanne (Switzerland), Radboud University (The Netherlands), University of Oxford (UK),…
Read More
Genetic discovery could lead to better prediction of suicide risk within families
Every 11 minutes, an American dies by suicide. That’s 132 people a day or more than 48,000 annually. For those left behind, the haunting question is why. One emerging factor is family history. Perhaps the most famous example is Ernest…
Read More
Researchers reveal how genetic variations are linked to COVID-19 disease severity
Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren’t sure why some people experience mild to no symptoms while others become critically ill. New research led by Robert E. Gerszten, MD, Chief of…
Read More
Major new study unveils complexity and vast diversity of Africa’s genetic variation
Africa is the cradle of humankind. All humans are descendants from this common pool of ancestors. Africa and its multitude of ethnolinguistic groups are therefore fundamental to learning more about humankind and our origins. A human genome refers to the…
Read More
Genetic risk for fatal blood clots identified in IBD patients
Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD)—ulcerative colitis or Crohn’s disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic…
Read More
Uncovering genetic roots of marijuana use disorder
A large study exploring possible genetic influences on cannabis use disorder has identified two regions in our DNA — one newly identified and a second that replicates a past finding — that appear to contribute to one’s risk of becoming…
Read More
New genetic analysis method could advance personal genomics
Geneticists could identify the causes of disorders that currently go undiagnosed if standard practices for collecting individual genetic information were expanded to capture more variants that researchers can now decipher, concludes new Johns Hopkins University research. The laboratory of Johns…
Read More
GTEx findings reveal genetic regulatory variation across tissues and cell types
The multi-institutional Genotype-Tissue Expression (GTEx) Consortium, in a final-phase initiative co-led by Tuuli Lappalainen, Ph.D., Core Faculty Member at the New York Genome Center, has published its final set of studies. The new research presents a comprehensive atlas that maps…
Read More