Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish’s lab to find solutions to a diverse set of biological problems. Originally created as a way to understand interactions between different…
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Researchers discover how a genetic mutation in mice and monkeys interferes with viruses
A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola. They say the finding…
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Researchers develop the smallest CRISPR to date for genome editing
A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell. This…
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Gene involved in male infertility discovered
A gene that controls the completion of meiosis in spermatogenesis has been discovered by researchers from Kumamoto University. Until now, details of the mechanism that inactivates the expression of genes involved in the meiotic program during spermatogenesis had not been…
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Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain
Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is. The findings could lead to more effective…
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Gene therapy protects optic nerve cells and preserves vision in glaucoma mouse models
A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH's National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading…
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PerkinElmer to buy SIRION Biotech
PerkinElmer Inc. (PKI) agreed to buy SIRION Biotech GmbH, a provider of viral vector-based technologies that drive improved delivery performance for cell and gene therapies. The acquisition is expected to close during the third quarter of 2021. Headquartered in Munich,…
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Researchers develop new method to make CRISPR gene editing more precise
CRISPR Researchers from Aarhus University and University of Copenhagen have developed a new method, which makes CRISPR gene editing more precise than conventional methods. The method selects the molecules best suited for helping the CRISPR-Cas9 protein with high-precision editing at…
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Defective gene slows down brain cells
Within the European Union alone, about 3 million people are affected by an autism spectrum disorder (ASD). Some are only mildly affected and can live independent lives. Others have severe disabilities. What the different forms have in common is difficulty…
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Scientists find gene mutation linked to exfoliation syndrome, most common cause of glaucoma
A team of researchers from the Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene)…
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