Researchers have uncovered a previously unknown arm of the immune defense system that protects the lung from lethal viral infections. Respiratory diseases caused by viruses such as influenza A and SARS-CoV-2 cause damage not just through their own actions, but…
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Study: 94% of older adults prescribed fall-risk-increasing drugs
Nearly every older adult was prescribed a prescription drug that increased their risk of falling in 2017, according to new University at Buffalo research. The study found that the percentage of adults 65 and older who were prescribed a fall-…
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A new type of recyclable: Finding new uses for established drugs
Discovering and treating tumors before they spread throughout the body is key for cancer patients to achieve positive outcomes. When tumor cells spread, which is known as metastasis, they can take over other organs and lead to death. Oral and…
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Organ-on-chip consortium receives huge grant to develop a universal standard for pharmaceutical industry
Scientists are pushing ahead building ‘organ-on-chips’, small chips with human cells, which are useful, for example, for studying cancerous metastases in the bloodstream or the development of scar tissue, or for testing the effect of drugs or food outside a…
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New inhibitor makes drug-resistant tumor cells respond again to chemotherapy
A new substance could improve the treatment of persistent cancers. Researchers at Martin Luther University Halle-Wittenberg (MLU) and the University of Greifswald have developed a new inhibitor that makes drug-resistant tumor cells respond again to chemotherapy. The new substance blocks…
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Studies reveal the promise of newly engineered bispecific antibodies against tumor cells
Three studies – one each in Science, Science Translational Medicine, and Science Immunology – reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases….
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Researchers identify drugs with potential to stop plaque buildup in arteries
Glycomics researchers at the University of Alberta and CHU Sainte-Justine have reported a discovery that could lead to new treatments for cardiovascular disease. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process…
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From trippy drugs to therapeutic aids – how psychedelics got their groove back
For many years, drugs such as LSD, psilocybin and Dimethyltryptamine (DMT) were viewed only as highly dangerous drugs. However, in recent years they have had a bit of rebrand. Now they’re believed by some to have the power to heal,…
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Novel hybrid device to boost research on metastatic process of breast cancer cells
European researchers are working on a novel hybrid device to better understand the metastatic process of cancer cells traveling from breast to bone and fast screen new drugs against it. The spread of cancer cells to other parts of the…
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Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, serious efforts have been made to identify new or repurposable drugs that effectively inhibit or counteract the infection. A…
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