In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia,…
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Drug found to correct gene defect that causes immune-driven gut leakiness
A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can repair…
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Scientists identify promising new ALS drug candidates
Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease. Researchers from the Universities of Liverpool (UK) and Nagoya (Japan) have shown that a Selenium-based drug-molecule called…
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Potential drug target revealed to help more children survive a lethal heart defect
When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before age 25. Now,…
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Drug target for aggressive breast cancer found
A team of British and American scientists have discovered a way to slow the growth of breast cancer stem cells in the lab. The study led by Dr. Bruno Simões and Professor Rob Clarke from The University of Manchester could…
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Mysterious brain structure sheds light on drug addiction
Do you remember where you were when you first heard that two planes had crashed into New York’s Twin Towers? Or where you had your first kiss? Our brains are wired to retain information that relates to the context in…
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Malaria drug chloroquine does not inhibit SARS-CoV-2
More than 600,000 people worldwide have fallen victim to the lung disease COVID-19 so far, which is caused by the SARS coronavirus-2 (SARS-CoV-2). In order to obtain an effective therapy for COVID-19 as quickly as possible, drugs that are being…
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Researchers identify possible drug target for prostate cancer
Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases. Castration-resistant prostate cancer is a highly aggressive form of prostate cancer that often leads…
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Computer guided drug delivery developed for brain disorders
While we are starting to get a handle on drugs and therapeutics that might to help alleviate brain disorders, efficient delivery remains a roadblock to tackling these devastating diseases. New research from the Graybiel, Cima, and Langer labs at MIT…
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Gilead’s $2,340 price for coronavirus drug draws criticism
The maker of a drug shown to shorten recovery time for severely ill COVID-19 patients says it will charge $2,340 for a typical treatment course for people covered by government health programs in the United States and other developed countries….
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