Scientists have identified a way to “rescue” muscle cells that have genetically mutated, paving the way to a possible new treatment for rare childhood illness such as Duchenne Muscular Dystrophy (DMD). The study, led by the Universities of Exeter and…
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Insights into the role of DNA repair and Huntington’s disease gene mutation open new avenues for drug discovery
Recent genetic data from patients with Huntington’s disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals who carry the expanded CAG repeat in the HTT gene that causes…
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Discovery of a new drug for diabetic retinopathy
A potentially effective treatment for diabetic retinopathy, a disease that swells and scars the retina, has been developed by an Université de Montréal scientist and investigator at Maisonneuve-Rosemont Hospital Research Centre (MRH-RC). Working with research scientist Pam Tsuruda of the…
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Drug trial that could improve respiratory recovery from COVID-19 now underway
A clinical trial has commenced this week to test whether a drug called Almitrine can help people who are seriously ill with COVID-19 to recover from the disease. Patients suffering from COVID-19 pneumonia often develop very low levels of oxygen,…
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Potential combined drug therapy for lung cancer
Most lung cancers are of a type called non-small-cell lung carcinoma (NSCLC). This type of cancer is relatively insensitive to chemotherapy, so NSCLC therapies are usually based on drug treatment. Alectinib is a drug commonly used for treating patients with…
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Proposing a new drug to treat tuberculosis utilizing state-of-the-art computer simulations
The research team of the Department of Computer Science and Engineering at the Toyohashi University of Technology and the Institute of Food Biotechnology and Genomics at the National Academy of Sciences of Ukraine have proposed a new drug to treat…
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Researchers discover new inhibitor drug combination for rare form of cancer
Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell…
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New drug combination could improve glucose and weight control in diabetes
Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical studies…
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Surgical and drug treatment options lead to similar outcomes for diabetic eye disease
Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy (PDR), according to a National Eye Institute (NEI)-supported clinical study from the DRCR Retina Network (DRCR.net). A consequence of diabetes, PDR…
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AstraZeneca buying drug developer Alexion for $39 billion
Pharmaceutical company AstraZeneca says it is buying U.S. drug developer Alexion in a deal worth $39 billion. Cambridge, England-based AstraZeneca PLC, which is involved in one of the efforts to develop a COVID-19 vaccine, said Saturday it’s using a combination…
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