Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues. The team, led by Professor Ken-ichiro Seino of Hokkaido University’s Institute for Genetic Medicine, found that thymic epithelium cells derived from…
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Novel communication between intestinal microbes and developing immune cells in the thymus
Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing…
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Breakthrough as scientists find how cancer-killing cells are activated
Cancer breakthrough as scientists discover how ‘helper’ cells are turned on by immunotherapy to destroy malignant tumours Some cells, known as CD4+ T cells, directly target tumours after immunotherapy But exactly how their cancer-killing powers were unlocked remained a mystery…
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