A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments….
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One way to prevent cancer: Map the fundamentals of how cells go awry
Someday, scientists may be able to prevent cancer by controlling two proteins that operate deep inside the quagmire of epigenetic cell fate transitions, a new paper suggests. Published by Nature Communications, the article describes a dynamic push and pull between…
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New 3-D model of a DNA-regulating complex in human cells provides cancer clues
Scientists have created an unprecedented 3-dimensional structural model of a key molecular “machine” known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and some other diseases. The researchers, led by Cigall Kadoch, Ph.D., of…
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Severe COVID-19 infection linked to overactive immune cells
Samples from the lungs of patients show a runaway immune system reaction could be one mechanism behind severe COVID-19 cases. When infected with the SARS-CoV-2 coronavirus, many people experience mild and moderate symptoms, but for some people infection can be…
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Spinal cord stem cells can help repair after injury
Spinal cord injury often leads to permanent functional impairment. In a new study published in the journal Science researchers at Karolinska Institutet in Sweden show that it is possible to stimulate stem cells in the mouse spinal cord to form…
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Senescent cells may be good when it comes to a bad injury
It’s called senescence, when stressed cells can no longer divide to make new cells, and it’s considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a younger age at least,…
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Researchers identify key role of immune cells in brain infection
A new study has detailed the damaging role played by the immune system in a severe brain condition most commonly caused by the cold sore virus. Researchers have identified the specific type of immune cell that induces brain inflammation in…
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Unconventional T cells in severe COVID-19 patients could predict disease outcome
Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells. The study, published today in the Journal of Experimental Medicine (JEM), suggests that monitoring the activity…
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Researchers identify RNA molecule that helps lung cancer cells evade immune system
Researchers in Spain have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body’s immune cells. The study, which will be published August 27 in the Journal of Cell Biology (JCB), suggests that…
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The secret of lymph: How lymph nodes help cancer cells spread
For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) provides insight into…
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