Aging-US published "Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma" which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA…
Read MoreEU Panel Endorses Duvelisib for CLL and Follicular Lymphoma
European Union approval has been recommended for duvelisib (Copiktra) for patients with relapsed/refractory chronic lymphocytic leukemia (CLL) or refractory follicular lymphoma (FL) who have received at least two prior lines of therapy. The European Medicines Agency’s Committee for Medicinal Products…
Read MoreSerum Biomarkers of Increased Risk for Second Primary Lung Cancer Identified
NEW YORK (Reuters Staff) – Using serum metabolomics profiling, researchers have identified two metabolites that are associated with risk for second primary lung cancer (SPLC) among survivors of initial primary lung cancer (IPLC). Lung cancer survivors are at high risk…
Read MoreLiquid Biopsy After Hepatectomy Promising Aid in Metastatic Colorectal Cancer
NEW YORK (Reuters Health) – Liquid biopsy following resection of colorectal liver metastases allows non-invasive molecular profiling which may help spot hard-to-detect remaining disease, according to Houston-based researchers. Dr. Yun Shin Chun told Reuters Health by email that analysis of…
Read MoreDelayed Start of HIV Therapy Tied to Small Increase in Risk of AIDS-Related Cancers
NEW YORK (Reuters Health) – Delaying the initiation of antiretroviral therapy (ART) in HIV-positive patients is associated with a small increase in risk for AIDS-related cancer, according to new research that supports long-standing guidance to start ART immediately regardless of…
Read MoreNew ASH Guidelines: VTE Prevention, Treatment in Cancer Patients
New guidelines from the American Society of Hematology “strongly recommend” using no thromboprophylaxis over using parenteral thromboprophylaxis in ambulatory patients receiving cancer chemotherapy who have low venous thromboembolism (VTE) risk, and using no thromboprophylaxis over oral thromboprophylaxis with vitamin K…
Read MoreResearchers Approach Publishers About Errors in 31 Papers
Retraction Watch readers may recall the name Jennifer Byrne, whose work as a scientific sleuth we first wrote about four years ago, and have followed ever since. In a new paper in Scientometrics , Byrne, of New South Wales Health Pathology and the University of…
Read MoreGERD Tied to Higher Risk of Cancer of the Larynx, Esophagus
NEW YORK (Reuters Health) – Gastroesophageal reflux disease (GERD) is associated with a higher risk of squamous cancers of the larynx and esophagus, according to results of a large prospective study. Roughly 17% of these cancers may be linked to…
Read MoreXenograft model for invasive lobular carcinoma simulates tumor with high accuracy
Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast. It covers 10-15% of all breast cancer cases, has a high risk of late recurrence, unique metastatic sites, high sensitivity…
Read MoreCancer Warning Labels on Alcohol: Calls for Congress to Act
At a time when Americans are drinking more alcohol than ever before, a group of health organizations is lobbying Congress for a new cancer-specific warning label to be displayed on all alcoholic beverages. The new wording would read: “WARNING: According…
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