A new study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy treatment in a manner that is similar to patients without that mutation, a discovery that runs counter to previous…
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Esophageal cancers resurrect ancient retroviruses hidden in our genome
Scientists have discovered that many esophageal cancers turn on ancient viral DNA that was embedded in our genome hundreds of millions of years ago. “It was surprising,” says Adam Bass, MD, the Herbert and Florence Irving Professor of Medicine at…
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Personalized cancer vaccines for breast, pancreatic cancers show promise
The COVID-19 vaccines — designed using bits of genetic information that prime our immune systems to recognize and fight off viral infections — have become lifesavers in the global fight to end the pandemic. Now, new research from Washington University…
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Studies suggest people with blood cancers may not be optimally protected after COVID-19 vaccination
Two new studies published in Blood suggest that the mRNA COVID-19 vaccine may have reduced efficacy in individuals with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer. According to researchers, these studies could help inform the…
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Drug could be a ‘game-changer’ in fighting esophageal cancers
Patients who have surgery for esophageal cancer commonly see the disease return, but a drug that boosts the immune system may help delay or prevent that, a new trial has found. The drug, called Opdivo (nivolumab), doubled the amount of…
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New guidelines for histiocytosis clarify best practices for recently-defined cancers
The National Comprehensive Cancer Network (NCCN)—an alliance of leading cancer centers—today announced the publication of new NCCN Guidelines for Histiocytosis. Histiocytoses are rare disorders characterized by a buildup of white blood cells called histiocytes, which leads to tissue damage. This…
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Untangling cancer’s complexity with Mission Bio’s true multi-omics Tapestri Platform
Insofar as the war on cancer used to be fought by surgical strikes, chemical warfare and nuclear bombardment, today’s and tomorrow’s cancer battles are fought through information warfare. The treatment of blood cancers, in particular, has a deep history of…
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Combining two precision medicines can treat drug-resistant cancers
Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows. It is the first trial to use the pioneering genetically targeted drug olaparib—already licensed…
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Personal use of permanent hair dye not associated with greater risk of most cancers or cancer death: study
Women who use permanent hair dye products to color their hair at home do not experience greater risk of most cancers or greater cancer related mortality, finds a study published by The BMJ today. While this should provide general reassurance…
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Researchers probe cancer’s ongoing evolution
Cancers gain and lose large sections of chromosomes in some of their cells but not in others, a process that may indicate ongoing evolution and selection for preferred traits, report a team of researchers led by the Max Delbrück Center…
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