NEW YORK (Reuters Health) – Pooled clinical-trial data show that teprotumumab improves eye bulging and double vision in patients with active thyroid eye disease, with most patients having long-lasting responses. The data clearly show that teprotumumab “mitigates varying levels of…
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EU Panel Endorses Duvelisib for CLL and Follicular Lymphoma
European Union approval has been recommended for duvelisib (Copiktra) for patients with relapsed/refractory chronic lymphocytic leukemia (CLL) or refractory follicular lymphoma (FL) who have received at least two prior lines of therapy. The European Medicines Agency’s Committee for Medicinal Products…
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Could Tamoxifen Dose Be Slashed Down to 2.5 mg?
Tamoxifen has long been used in breast cancer, both in the adjuvant and preventive setting, but uptake and adherence are notoriously low, mainly because of adverse events. Using a much lower dose to reduce the incidence of side effects would…
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IDSA Updates COVID-19 Treatment Guidelines: Monoclonals and More
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. While there is still no “game-changer” for treating COVID-19, the Infectious Diseases Society of America (IDSA) continues to examine available and potential treatments as new evidence…
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Mitochondrial DNA Variant Increases Gallstone Risk
A mitochondrial DNA variant may increase the risk of gallstone disease more than fourfold, according to investigators. Mitochondrial DNA 827A>G disrupts mitochondrial function and leads to abnormal cholesterol transport, which increases gallstone development, reported Dayan Sun, of Fudan University, Shanghai,…
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Researchers Approach Publishers About Errors in 31 Papers
Retraction Watch readers may recall the name Jennifer Byrne, whose work as a scientific sleuth we first wrote about four years ago, and have followed ever since. In a new paper in Scientometrics , Byrne, of New South Wales Health Pathology and the University of…
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UK to Prioritize Next Stage of COVID Vaccine by Age, Not Job
LONDON (Reuters) – Police and teachers will not jump to the head of the queue in the second phase of Britain’s COVID-19 vaccination rollout, with people instead prioritised by age, officials advising the government said on Friday, describing this as…
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