The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to rampant hospitalizations. The most at-risk populations for developing severe disease include – the elderly; infants and neonates; and individuals with pre-existing heart, respiratory, metabolic, and autoimmune…
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New monoclonal antibody shows promise for severe asthma
A new monoclonal antibody therapy shows promise in offering an alternative treatment for patients suffering from moderate-to-severe asthma. Research led by Michael E. Wechsler, MD, MMSc, director of the National Jewish Health Cohen Family Asthma Institute, found that itepekimab was…
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Study finds correlation between neutralizing antibody titer and reported vaccine efficacy
An observational study compares immune responses against three vaccines: BNT162b2 (Pfizer mRNA vaccine), mRNA-1273 (Moderna mRNA vaccine), and Ad26.COV2.S (J&J adenovirus vaccine). Study: Comparative analysis of human immune responses following SARS-CoV-2 vaccination with BNT162b2, mRNA-1273, or Ad26.COV2.S. Image Credit: DisobeyArt/…
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WHO recommends antibody treatment for COVID patients at high risk of hospital admission
A treatment combining two antibodies (casirivimab and imdevimab) is recommended for two specific groups of patients with COVID-19 by a WHO Guideline Development Group (GDG) panel of international experts and patients in The BMJ today. The first are patients with…
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Single protein is a key player in two very common forms of dementia, study reveals
Dementia has many faces, and because of the wide range of ways in which it can develop and affect patients, it can be very challenging to treat. Now, however, using supercomputer analysis of big data, researchers from Japan were able…
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New hope for antibody to treat muscular dystrophy
Northwestern Medicine scientists have developed an antibody that they believe can be used to treat muscular dystrophy, findings that were published in Science Translational Medicine. “We believe this can become a therapy for muscular dystrophy, including the many different forms…
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Immunological differences in Moderna and Pfizer-BioNTech vaccine-induced Fc-functional profiles
The perseverance of scientists worldwide has led to the rapid development of many SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) vaccines and provided preventative measures against the coronavirus 2019 (COVID-19) pandemic. However, there have been many cases of breakthrough infections,…
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COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants
COVID-19 vaccination elicited antibody responses in nearly nine out of 10 people with weakened immune systems, although their responses were only about one-third as strong as those mounted by healthy people, according to a study by researchers at Washington University…
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Pfizer CEO to public: Just trust us on the covid booster
Pfizer CEO Albert Bourla was confident in June about the ability of his company's vaccine to protect against the highly contagious delta variant, as it marched across the globe and filled U.S. hospitals with patients. "I feel quite comfortable that…
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The antibody with a secret: Scientists uncover IgA antibodies ability to fight malaria
Antibodies have drawn a spotlight over the past year and a half as scientists and lay people alike have asked how long the infection-fighting proteins persist in the face of a formidable enemy—a pandemic virus that has been transmitted on…
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