Researchers in the United States have developed an alternative messenger RNA (mRNA) delivery platform to the lipid nanoparticles that are currently used in vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019…
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Experimental evidence that ADAM17 inhibition prevents severe COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus that is contagious in humans. It is the causal agent of the ongoing coronavirus 2019 (COVID-19) pandemic. This virus causes a mild to severe infection and has…
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Broadly cross-reactive antibody to SARS-CoV-2 RBD with robust resistance to mutational escape
The current pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered an intensive hunt for effective new and repurposed antivirals and antibodies, for prevention and treatment of the infection. A new preprint…
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Researchers discover a new monoclonal antibody that is effective against SARS-CoV-2 variants
A new monoclonal antibody targets a particular region of the receptor-binding domain (RBD) on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This region is usually not accessible to immune cells, which may be why it has broad neutralizing capabilities….
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Comorbidities lead to an increased risk of death from Covid-19, research shows
Comorbidities such as heart disease, respiratory disease, renal disease and cancer lead to an increased risk of death from Covid-19 according to new research from the University of East Anglia (UEA) and the Norfolk and Norwich University Hospital (NNUH). Image…
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Novel host-viral-microbiome interactions during COVID-19 may determine outcome
The current pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been spreading rapidly for over a year. Though primarily a respiratory illness, its manifestations are often protean and may be life-threatening….
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Concerning mutation in New York SARS-CoV-2 should be monitored, warn researchers
Researchers at the New York State Department of Health in the United States have said concerning mutations within the B.1.526 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently become prevalent in New York State warrant further…
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Polyphenols may provide protective effect against COVID-19 disease
According to the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU), as of today, February 22nd, 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 111 million individuals worldwide. COVID-19 disease, caused by…
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Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, serious efforts have been made to identify new or repurposable drugs that effectively inhibit or counteract the infection. A…
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Amlodipine/Valsartan/HCT Novartis
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. VALSARTAN/AMLODIPINE/HCT NOVARTIS® 5/160/12.5, 5/160/25, 10/160/12.5, 10/160/25, 10/320/25 amlodipine besilate/valsartan/hydrochlorothiazide Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about AMLODIPINE/VALSARTAN/HCT NOVARTIS. It…
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