The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy. Called Type 1 diabetes, this disorder can occur at any age and…
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Non-invasive imaging method can predict the efficiency of cardiomyocyte differentiation
Stem cell research holds great potential for regenerative therapies and treatments to combat cardiovascular disease, which is responsible for over 30% of all deaths worldwide. Highly functional cardiomyocytes-;the muscle cells responsible for the contraction of the heart-;are important for disease…
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New method for growing embryos outside the womb
To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought grail…
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A region within GLI1 gene could potentially be targeted as cancer treatment
Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene's expression. These findings,…
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Scientists study how a single gene alteration may have separated modern humans from extinct hominins
As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders. For almost as…
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New research aims to explore functions of bile acids in the gut stem cell niche
Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant piece of the puzzle. Image Credit: Flinders University Associate…
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Hematopoiesis Regulators
Hematopoiesis is the process of blood cell renewal in the body and occurs throughout adulthood. Growth factors enable the tight regulation of hematopoiesis, enabling new blood cells to differentiate, proliferate, and mature. YAKOBCHUK VASYL | Shutterstock Blood cells have various…
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Driving Stem Cell Differentiation in Teeth using a Hardened Polymer Matrix
Dental root voids are commonly obturated with polymer materials that harden after injection. Research is exploring the use of hydrogels seeded with pluripotent stem cells to regenerate the natural tooth material from the inside of the filling, instead of gluing…
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