A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), also takes place in the brains of…
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Adaptive brain response to stress—and its absence—in people with depression
A new study identifies a novel biomarker indicating resilience to chronic stress. This biomarker is largely absent in people suffering from major depressive disorder, and this absence is further associated with pessimism in daily life, the study finds. Nature Communications…
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How a faster WHO response could have slowed COVID-19’s spread
Urgent global action is needed to end the COVID-19 pandemic and prepare for future threats, according to a new report by the Independent Panel for Pandemic Preparedness and Response. The panel, co-chaired by former New Zealand prime minister Helen Clark…
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Mimicking a chronic immune response changes the brain
As March comes around, many people experience hay fever. As excessive immune responses go, most would admit that hay fever really isn’t that bad. At the other end of the spectrum are severely debilitating autoimmune diseases like rheumatoid arthritis and…
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Public Health Officials Face Wave Of Threats, Pressure Amid Coronavirus Response
Emily Brown was stretched thin. As the director of the Rio Grande County Public Health Department in rural Colorado, she was working 12- and 14-hour days, struggling to respond to the pandemic with only five full-time employees for more than…
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Gene could help predict response to cervical cancer treatment
UCLA researchers have identified a potential diagnostic marker that could help predict how likely someone with cervical cancer is to respond to the standard treatment of chemotherapy and radiation. The scientists found that PACS-1, a gene that resides on a…
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New polio vaccine against strain that threatens eradication is safe and generates immune response
Phase 2 trials in 1,200 adults, young children, and infants suggest new poliovirus vaccine may have the potential to overcome outbreaks caused by a mutated polio strain linked to the oral vaccine that typically circulates in areas of low immunisation…
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Potential cancer therapy may boost immune response
A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by…
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Six pandemic profiles identified in study of public’s response to guidance
Researchers investigating the public response to official COVID-19 guidance say people can be split into six distinct groups determined by the way they search for, follow and act upon official advice. The profiles have been identified by social scientists at the University…
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Children produce different antibodies in response to SARS-CoV-2
Children and adults produce different types and amounts of antibodies in response to infection with the new coronavirus, SARS-CoV-2, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found. The differences in antibodies suggest…
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