For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another. Individual transporter particles…
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Sample Preparation for Fluorescence Microscopy
By Shelley Farrar, MSc, BSc Fluorescence Microscopy allows specimens to be studied with high sensitivity and specificity through the use of light. It works on the principle that energy emitted by certain types of materials can be detected as light,…
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What is Binding Activated Localization Microscopy (BALM?)
In the field of super-resolution microscopy, single-molecule localization microscopy (SMLM) is a fast-evolving technique that allows researchers to study subcellular structures and the dynamics of single molecules at the nanoscale. SMLM works by isolating single fluorescent molecules from each other…
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