California and Texas, the country's two most populous states, have taken radically different approaches to the pandemic and the vaccination campaign to end it. California has trumpeted its reliance on science and policies it says are aimed at improving social…
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Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain
Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain – an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by…
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Sexually active individuals under age 30 should be tested for chlamydia and gonorrhea
Anyone sexually active under age 30 should be offered testing for chlamydia and gonorrhea, according to a new guideline from the Canadian Task Force on Preventive Health Care published in CMAJ (Canadian Medical Association Journal). Chlamydia and gonorrhea are the…
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New machine learning method for designing more effective antibody drugs
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies are extremely…
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Altering a mosquito's gut genes shows promise to curb malaria
Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife. The study is the latest in…
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Targeted therapy achieves excellent outcomes, reduces side effects in high-risk Hodgkin lymphoma
Scientists are reporting results of the first frontline clinical trial to use targeted therapy to treat high-risk pediatric Hodgkin lymphoma. The study showed that the addition of brentuximab vedotin achieved excellent outcomes, reduced side effects, and allowed for reduced radiation…
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For this hospice nurse, the Covid shot came too late
Antonio Espinoza loved the Los Angeles Dodgers. He loved them so much that he was laid to rest in his favorite Dodgers jersey. His family and friends, including his 3-year-old son, donned a sea of blue-and-white baseball shirts and caps…
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Discovering DNA methylation from bacteria and microbiome using nanopore technology
Journal name: Nature Methods Title of the article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing Corresponding author: Gang Fang, PhD Bottom line: Bacterial DNA methylation occurs at diverse sequence contexts and plays important…
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Harnessing previous research to mitigate the mental health impacts of COVID-19 on adolescents
A team of researchers has sought to mitigate the mental health impacts of COVID-19 on adolescents by harnessing previous research on youth physical and mental health. Their review also drew on the psychological stressors of the 2011 Great East Japan…
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Scientists discover new genetic disease that causes abnormal brain development in children
Scientists have discovered a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts. The majority of patients with the condition, which is so new it doesn't have a…
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