CHICAGO ― The long-term side effects of hypofractionated postoperative prostate bed radiotherapy (HYPORT) for prostate cancer are similar to those of conventional radiotherapy, a new study concludes. “Hypofractionation is a strategy for shortening treatment by giving larger doses per fraction…
Read MoreShock, Disbelief as NCCN Changes Prostate Cancer Guidance
For over a decade, the influential National Comprehensive Cancer Network (NCCN) has been recommending that men with low-risk prostate cancer be offered active surveillance as the lone “preferred” initial treatment option. But the NCCN has now reversed this long-standing recommendation…
Read MoreLuminal, Basal Groupings Could Change Metastatic Prostate Ca Tx
Metastatic castration resistant prostate cancer (mCRPC) can be classified as either luminal or basal and, as in primary tumors, the distinction has important prognostic and therapeutic implications, concludes a new report in JAMA Oncology. Furthermore, the classification is “an important…
Read MoreProstate Cancer Surgeries Plummeted for Black Men in 2020
During the initial COVID-19 lockdown, the odds of Black men undergoing surgery for untreated nonmetastatic prostate cancer dropped by 94%, but for White men, there was no change, new data show. Before the pandemic, “there was no difference between White…
Read MorePromising immunotherapy uses cancer-killing cells to destroy malignant tumors
Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors. The modified "natural killer" cells can differentiate between cancer cells and healthy cells that…
Read MoreLoneliness in Middle-Aged Men Linked to Increased Cancer Risk
Loneliness among middle-aged men ups their risk of cancer, and being single at the time of diagnosis confers a worse prognosis, suggest results from a longitudinal Finnish study with a mean follow-up of 20 years. The study also found that…
Read MoreScientists identify new biomarkers in patients with malignant melanoma, which could help in its diagnosis and prognosis
A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant…
Read MorePhase 3 DREAM3R trial opens for malignant pleural mesothelioma
The DREAM3R phase three clinical trial is now enrolling patients with newly diagnosed unresectable malignant pleural mesothelioma (MPM) throughout the US, Australia, and New Zealand. The DREAM3R study builds on signals of effectiveness found in independent single-arm phase two trials,…
Read MoreStudies reveal the promise of newly engineered bispecific antibodies against tumor cells
Three studies – one each in Science, Science Translational Medicine, and Science Immunology – reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases….
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