Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife. The study is the latest in…
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Exercise could be used to improve the oral environment in people with NAFLD
Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut. Bacteria that cause inflammation in the mouth are transported through the digestive tract to the gut…
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Discovering DNA methylation from bacteria and microbiome using nanopore technology
Journal name: Nature Methods Title of the article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing Corresponding author: Gang Fang, PhD Bottom line: Bacterial DNA methylation occurs at diverse sequence contexts and plays important…
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International team identifies genetic link between face and brain shape
An interdisciplinary team led by KU Leuven and Stanford has identified 76 overlapping genetic locations that shape both the face and our brain. What the researchers didn’t find is evidence that this genetic overlap also predicts someone’s behavioral-cognitive traits or…
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A single injection reverses blindness in patient with rare genetic disorder
A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye. The clinical trial was conducted by researchers at…
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Scientists discover new genetic disease that causes abnormal brain development in children
Scientists have discovered a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts. The majority of patients with the condition, which is so new it doesn't have a…
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New approach can help identify patients at risk for esophageal cancer
A combination of esophageal brushing and extensive genetic sequencing of the sample collected can detect chromosome alterations in people with Barrett's Esophagus, identifying patients at risk for progressing to esophageal cancer, according to a new study by researchers at the…
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Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown
Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two…
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Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis
In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases (CRID), linked to the University of São Paulo (USP) in Brazil, discovered a novel path in…
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New method for growing embryos outside the womb
To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought grail…
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