As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders. For almost as…
Read MoreResearchers discover previously-unknown function in enzyme critical for cancer growth
Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to keep cancer…
Read MoreInsights into the role of DNA repair and Huntington’s disease gene mutation open new avenues for drug discovery
Recent genetic data from patients with Huntington’s disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals who carry the expanded CAG repeat in the HTT gene that causes…
Read MoreModified CRISPR/Cas9 complex targets specific histones
Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle. Rice University researchers have achieved something of the sort with a new genome editing tool that targets the supporting players in a…
Read MoreResearchers explore link between ‘Alzheimer’s gene’ and COVID-19
A City of Hope-led research team found that the same gene that increases the risk for Alzheimer’s disease, ApoE4, can increase the susceptibility to and severity of COVID-19. “Our study provides a causal link between the Alzheimer’s disease risk factor…
Read MoreAbacavir/Lamivudine 600/300 APOTEX
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ABACAVIR/LAMIVUDINE 600/300 APOTEX TABLET Contains the active ingredients abacavir (as sulfate) and lamivudine Consumer Medicine Information PATIENTS TAKING ABACAVIR AND LAMIVUDINE COMBINATION TABLETS, WHICH CONTAINS ABACAVIR, MAY…
Read MoreSample Preparation for Fluorescence Microscopy
By Shelley Farrar, MSc, BSc Fluorescence Microscopy allows specimens to be studied with high sensitivity and specificity through the use of light. It works on the principle that energy emitted by certain types of materials can be detected as light,…
Read MoreAlecensa
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ALECENSA® ROCALECE10720 alectinib hydrochloride Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Alecensa. It does not contain all the available…
Read MoreRegulation of Gene Expression
Gene expression can be regulated by various cellular processes with the aim to control the amount and nature of the expressed genes. Expression of genes can be controlled with the help of regulatory proteins at numerous levels. These regulatory proteins…
Read MoreWhat are Viral Retroposons?
By Gillian D’Souza, MSc Retroposons are repetitive DNA fragments that are inserted into a host chromosome after reverse transcription from an RNA molecule. Credit: Katryna Kon/Shutterstock.com Retroposons that share structural similarities with retroviruses, such as the HIV virus, are called…
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