A team of researchers working at the Indiana University School of Medicine, has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, the group describes their work in attempting…
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LSL60101 compound reduces neuroinflammation and improves cognition
The LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies against Alzheimer’s disease. This is stated in the recent studies by the Research Group on Medicinal Chemistry and…
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Nutrient compound shows promise for halting mother-to-fetus Zika transmission
Before COVID-19, there was another public health crisis that captured headlines around the world: the Zika virus outbreak of 2015-16, which became an epidemic as it spread through Brazil and the Americas. The mosquito-borne virus was perhaps best known for…
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Researchers identify SARS-CoV-2 antiviral compounds using protein assay
On March 11, 2020, the World Health Organization (WHO) announced the coronavirus disease 2019 (COVID-19) to be a pandemic. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, which is deemed to be highly contagious…
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Compound isolated from human sperm could treat genetic disorder
A newly discovered genetic condition caused by faulty protein synthesis which causes delayed development and learning difficulties could be treated by a compound originally isolated from human sperm, say scientists. The University of Manchester researchers, with collaborators from the UK,…
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Sample Preparation for Fluorescence Microscopy
By Shelley Farrar, MSc, BSc Fluorescence Microscopy allows specimens to be studied with high sensitivity and specificity through the use of light. It works on the principle that energy emitted by certain types of materials can be detected as light,…
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Drug Repurposing: Biomedical Tools and Research Techniques
Most drugs are develooped with a specific indication, without ever investigating the efficacy against other diseases. This article describes the benefits of drug repurposing over traditional drug development, and the scientific methods used to identify new uses of a drug….
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Bouillon fortified with a new iron compound could help reduce iron deficiency
Iron fortification of food is a cost-effective method of preventing iron deficiency. But finding iron compounds that are easily absorbed by the intestine without compromising food quality is a major challenge. Now, studies from Chalmers University of Technology, ETH Zurich…
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