People who have previously been treated for a type of bowel cancer that has spread to other parts of their body will now have another treatment option in England, following the approval of the combined use of nivolumab (Opdivo) and…
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Discovery of potential new combination therapy for leukemia
WEHI researchers have discovered why some leukemia cells are resistant to new “SMAC-mimetic’ anti-cancer agents, a finding which could improve the use of these drugs in the clinic. The team discovered that the ‘drug pump’ protein MDR1 makes acute myeloid…
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Researchers discover new inhibitor drug combination for rare form of cancer
Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell…
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New drug combination could improve glucose and weight control in diabetes
Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical studies…
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Combination therapy might improve outcomes in treatment-resistant liver cancer
A combination cancer therapy that is effective against treatment-resistant hepatocellular carcinoma (HCC) by inhibiting tumor growth and increasing survival has been identified by researchers at Massachusetts General Hospital (MGH). In a paper published in the Journal for ImmunoTherapy of Cancer,…
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Baricitinib in Combination with Remdesivir Reduces Time to Recovery in Hospitalized Patients
INDIANAPOLIS, Sept. 14, 2020 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) and Incyte (NASDAQ: INCY) announced today initial data emerging from the Adaptive COVID-19 Treatment Trial (ACTT-2) sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National…
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Combination drug therapy for childhood brain tumors shows promise in laboratory models
In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either…
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