Researchers at the New York State Department of Health in the United States have said concerning mutations within the B.1.526 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently become prevalent in New York State warrant further…
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Children with MIS-C have highly activated immune systems, study finds
Taking the first deep dive into how the immune system is behaving in patients with multisystem inflammatory syndrome in children (MIS-C), researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have…
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Studies reveal the promise of newly engineered bispecific antibodies against tumor cells
Three studies – one each in Science, Science Translational Medicine, and Science Immunology – reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases….
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A region within GLI1 gene could potentially be targeted as cancer treatment
Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene's expression. These findings,…
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Researchers use Doppler to look inside living cells, track their metabolic activity
Doppler radar improves lives by peeking inside air masses to predict the weather. A Purdue University team is using similar technology to look inside living cells, introducing a method to detect pathogens and treat infections in ways that scientists never…
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Glycan switch may explain why SARS-CoV-2 causes such variable symptoms
Researchers in Portugal have provided evidence that might explain why infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes mild or even asymptomatic illness in some individuals, but severe coronavirus disease 2019 (COVID-19) in others. Salome Pinho from the…
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Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?
Rotavirus is a common diarrheal disease that affects young children. Live oral rotavirus vaccines have been used to reduce its incidence in many countries. However, with the onset of the coronavirus disease 2019 (COVID-19) pandemic, and amid focus on vaccines…
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Children exposed to air pollution may be at higher risk of disease in adulthood
Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study. The analysis,…
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Polyphenols may provide protective effect against COVID-19 disease
According to the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU), as of today, February 22nd, 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 111 million individuals worldwide. COVID-19 disease, caused by…
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Scientists reveal the structure of glutamate transporter in our cells
For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another. Individual transporter particles…
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