The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and…
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Study finds a significant link between statins and survival rates of triple-negative breast cancer patients
A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy…
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Cancer cell growth findings may hold promise for future cancer treatments
For a cell to grow and divide, it needs to produce new proteins. This also applies to cancer cells. In a new study published in Science Advances, researchers at Karolinska Institutet have investigated the protein eIF4A3 and its role in…
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Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas
Oncotarget published "TERT and its binding protein: overexpression of GABPA/B in high grade gliomas" which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas. In secondary glioblastomas after chemotherapy, GABPB1…
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Researchers identify an unexpected effect for already characterized active substances
Every innovative drug starts with the search for an active substance targeting key players in disease-related processes. However, there is no perfect drug that affects the one target in the body: no effect without side effects, as also described in…
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New live cell models lay the groundwork for studies into mitochondrial diseases
The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes. But when…
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Research provides an update on how electrical impulses in the heart travel from cell to cell
The rhythm in a working heart is regulated by electrical impulses. Disturbances of this bioelectrical process can result in cardiac arrhythmias, or irregularities in heartbeat — a common ailment that can lead to illness and death. In Biophysics Reviews, by…
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New study reveals how heparan sulfate promotes amyloid deposition in various organs
Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens in vital organs, such as the brain, kidney, liver and heart, it causes…
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Novel face mask can diagnose Covid-19 in 90 minutes
Engineers at MIT and Harvard University have designed a novel face mask that can diagnose the wearer with Covid-19 within about 90 minutes. The masks are embedded with tiny, disposable sensors that can be fitted into other face masks and…
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Induced pluripotent stem cells hold great promise for regenerative medicine
The 2012 Nobel prize-winning discovery that ordinary cells could be coaxed to revert to their earliest pluripotent stage ushered in the era of ethical stem cell research. Suddenly, scientists can have an inexhaustible supply of pluripotent stem cells — the…
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