According to Penn State College of Medicine researchers, the absence of a protein that works to prevent tumour formation may explain why some patients are resistant to common cancer therapy. They said that testing cancers for the presence of this…
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Scientists unlock promising key to preventing cancer relapse after immunotherapy
Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed…
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Cancer: Tumor driver promoting EMT, metastasis and resistance to therapy
Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant…
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How AI could make therapeutic decision-making for breast cancer more accurate, affordable
Imagine being a doctor and having a precocious resident permanently by your side, giving you brilliant insight into disease and helping you to identify the best treatment path for your patients. A team at Salesforce Research believes this scenario is…
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Gene could help predict response to cervical cancer treatment
UCLA researchers have identified a potential diagnostic marker that could help predict how likely someone with cervical cancer is to respond to the standard treatment of chemotherapy and radiation. The scientists found that PACS-1, a gene that resides on a…
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Potential cancer therapy may boost immune response
A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by…
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Cancer Risk Up Into Adulthood for Those With Birth Defects
FRIDAY, Dec. 4, 2020 — Individuals with birth defects have an increased risk for cancer, which persists into adulthood, according to a study published online Dec. 2 in The BMJ. Dagrun Slettebø Daltveit, from the University of Bergen in Norway,…
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Cancer-killing virus activates immune system against colon cancer
A cancer-killing virus that City of Hope scientists developed could one day improve the immune system’s ability to eradicate tumors in colon cancer patients, according to a new study in Molecular Cancer Therapeutics, a journal of the American Association for…
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Combination therapy might improve outcomes in treatment-resistant liver cancer
A combination cancer therapy that is effective against treatment-resistant hepatocellular carcinoma (HCC) by inhibiting tumor growth and increasing survival has been identified by researchers at Massachusetts General Hospital (MGH). In a paper published in the Journal for ImmunoTherapy of Cancer,…
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Getting it just right: The Goldilocks model of cancer
Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a…
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