Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy. Triple-negative breast cancer (TNBC) is the most aggressive form of…
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Statins: Cholesterol drug can now be used to fight another major killer – new study
Sarah Harding: Dr Hilary outlines breast cancer symptoms We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding….
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Breast cancer: Popular drug known to disrupt microbiome could be increasing your risk
Breast cancer is the most common type of cancer to be diagnosed in the UK, but it’s not always easy to know if you’re at risk. Worse still, you may be putting yourself at added risk by taking a popular drug almost…
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Study finds racial and ethnic disparities in post-operative breast cancer surgery outcomes
Breast cancer is the most commonly diagnosed cancer among American women and surgery is a primary treatment for these women. Among women receiving surgery, up to 13% will have a post-operative visit to an emergency department, according to recent research….
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Study finds a significant link between statins and survival rates of triple-negative breast cancer patients
A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy…
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Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients
In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers. The…
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Study: Genetic mutations associated with breast cancer risk are the same in Black and white women
The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson…
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Novel Gene Panel Predicts Who Can Skip RT in Early Breast Cancer
A novel 16-gene panel based on the biology of locoregional recurrence in early invasive breast cancer can both identify patients with a low risk of recurrence if they were to skip postsurgery radiation therapy, and predict which patients would be…
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Follow-Up Supports MammaPrint to Guide Chemo Decisions, Points to an ‘Age Effect’
NEW YORK (Reuters Health) – Longer-term follow-up data from the MINDACT trial confirm the clinical utility of the 70-gene MammaPrint assay to help guide chemotherapy decisions in women with early breast cancer, but also suggests that age may be a…
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Could Tamoxifen Dose Be Slashed Down to 2.5 mg?
Tamoxifen has long been used in breast cancer, both in the adjuvant and preventive setting, but uptake and adherence are notoriously low, mainly because of adverse events. Using a much lower dose to reduce the incidence of side effects would…
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