Brain cells called astrocytes play a key role in helping neurons develop and function properly, but there's still a lot scientists don't understand about how astrocytes perform these important jobs. Now, a team of scientists led by Associate Professor Nicola…
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MIND diet may benefit older adults, research shows
Aging takes a toll on the body and on the mind. For example, the tissue of aging human brains sometimes develops abnormal clumps of proteins that are the hallmark of Alzheimer's disease. How can you protect your brain from these…
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Study identifies a novel potential biomarker for hepatocellular carcinoma
Aging-US published "Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma" which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA…
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New insights into participation of underrepresented communities in Alzheimer’s clinical trials
A significant hurdle in developing therapeutics and care models for Alzheimer's disease that work for people of all ethnic and racial backgrounds is the recruitment and retention of traditionally underrepresented groups in clinical trials. At the Alzheimer's Association International Conference®…
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Research identifies key role of CXCL9 cytokine in age-related chronic inflammation
An inflammatory-aging clock called developed by Stanford University School of Medicine and the Buck Institute for Research on Aging can predict how strong your immune system will be in 10 years, when you'll become frail or whether you may develop…
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Nanomaterials' physiochemical properties influence their ability to penetrate the blood brain barrier
Nanomaterials found in consumer and health-care products can pass from the bloodstream to the brain side of a blood-brain barrier model with varying ease depending on their shape – creating potential neurological impacts that could be both positive and negative,…
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Desperate for home care, seniors often wait months with workers in short supply
For years, Louise Shackett has had trouble walking or standing for long periods, making it difficult for her to clean her house in southeastern Maine or do laundry. Shackett, 80, no longer drives, which makes it hard to get to…
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Increasing novel lncRNA in cardiomyocytes can inhibit the progression of heart failure
A research collaboration based in Kumamoto University (Japan) has identified a novel lncRNA, Caren, that is abundantly expressed in cardiomyocytes. They showed that it enhances energy production by increasing the number of mitochondria in cardiomyocytes, and inhibits activation of the…
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Aging impairs anti-tumor T-cell response via mitochondria dysfunction
MUSC Hollings Cancer Center researchers are finding solutions to the aging-related changes that reduce anti-cancer immunity. Besim Ogretmen, Ph.D., and colleagues found a novel link between aging, metabolism and anti-cancer T-cell function. Their work, published in Cell Reports, sheds light…
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Tsimane's brains experience less brain atrophy than Westerners as they age, indicates study
A team of international researchers has found that the Tsimane indigenous people of the Bolivian Amazon experience less brain atrophy than their American and European peers. The decrease in their brain volumes with age is 70% slower than in Western…
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