New therapeutics could help treat excess urine in the kidneys
Physiologists at the University of Nevada, Reno have identified two ion channels necessary for urine to flow from the kidneys to the ureters. A calcium-activated chloride channel and a voltage-dependent calcium channel are required for contractions to travel from the…
Read MoreHealthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year
In a recent study posted to the medRxiv* pre-print server, researchers conducted a community-based prospective cohort study in Managua, Nicaragua, before the beginning of the winter season when influenza A (H3N2) cases surge in the Northern Hemisphere. Study: High co-circulation…
Read MorePatients with refractory metastatic colorectal cancer experience survival benefits with fruquintinib
Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer. Findings from the global FRESCO-2…
Read MoreNCI Postdoc Faked Data, Says Federal Watchdog
A former postdoc at the National Cancer Institute faked 15 figures and a movie in grant applications, presentations, a paper, and an unpublished manuscript, according to a federal watchdog. The finding from the U.S. Office of Research Integrity (ORI) comes more than…
Read MoreNew technology offers pathways to finding treatments for kidney disease
Chronic kidney disease and eventual kidney failure are incurable diseases that affect 13% of the U.S. population, particularly those with high blood pressure and diabetes. These diseases degrade the “podocyte” cells of the kidney that maintain the body’s blood filtration…
Read MoreRET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population
The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center. Results from the tumor-agnostic cohort…
Read MoreEnergy Costs Alarm Britons Needing At-Home Kidney Care
LONDON (Reuters) – Sitting next to her dialysis machine which pumps clean blood around her body for four hours every day, Dawn White says she fears Britain’s spiralling energy costs means she will no longer be able to afford the…
Read MoreNearly 1 in 4 young US adults sought mental health care during pandemic
The stresses of the COVID-19 pandemic may have led to a significant jump in the number of young American adults seeking help for mental health woes, new data shows. Between 2019 and 2021, the percentage of American adults overall who…
Read MoreHeartbroken mum’s warning as son dies after Turkey weight loss surgery
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Read MoreStem cell-gene therapy shows promise in ALS safety trial
Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of…
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