3D map reveals DNA organization within human retina cells: Scientists shed light on how genetic architecture determines gene expression, tissue-specific function, and disease phenotype in blinding diseases

3D map reveals DNA organization within human retina cells: Scientists shed light on how genetic architecture determines gene expression, tissue-specific function, and disease phenotype in blinding diseases

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus. The resulting comprehensive gene regulatory network provides insights…

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