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People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer. Scientists led by the Department of Paediatrics at University Hospital Frankfurt have…

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and…

Several new clinical trials in colorectal cancer started recruiting in recent months. Maybe one of your patients could benefit from taking part. HER2+ metastatic and/or unresectable colorectal cancer. Patients in this position who have not received anti-HER2 therapy or any…

Researchers at Uppsala University in Sweden are using Integra Biosciences’ PIPETBOY pro pipette controllers with integrated LED lighting to study the physiological function of mast cells and their role in allergic reactions. Their ultimate aim is to develop novel vaccines and therapies…

Heart attacks at a glance Every year 56,700 Australians have a heart attack or angina, equating to 155 events every day. Twice as many men experience heart attacks as women, and considerably more men die. 93 percent more men are…

The study covered in this summary was published on medrxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway Adding chemotherapy to programmed cell death protein 1/programmed cell death-ligand 1 [PD-(L)1] blockade for first-line treatment of advanced…

Response to buprenorphine among emergency department (ED) patients using fentanyl was similar to that in patients using other opioids, based on data from nearly 900 individuals. California emergency departments include a facilitation program known as CA Bridge for the treatment…

People with sickle cell disease who receive nonmyeloablative stem cell transplants are at greater risk for developing new tumors, according to a new study published in the Journal of Clinical Oncology. Approximately 100,000 Americans have sickle cell disease, the most…

From 2014 to 2021, the rates of active surveillance for low-risk prostate cancer increased, but considerable practice- and practitioner-level variation is seen in its use, according to a study published online March 2 in JAMA Network Open. Matthew R. Cooperberg,…