Reviewers’ Notes Researchers are testing new combinations of drugs to treat breast cancer that’s spread to the bone, thanks to funding from Breast Cancer Now. The charity has awarded £142,714 to Professor Penelope Ottewell at the University of Sheffield, to…
Read MoreWomen with pre-eclampsia undergo accelerated aging during pregnancy
Reviewers’ Notes Pre-eclampsia, a life-threatening surge in blood pressure, is an enigmatic condition. Each year, it causes the deaths of more than 70,000 women worldwide. Because scientists do not know what causes it, they lack targeted strategies to treat it….
Read MoreWritten Exposure Therapy Matches Prolonged for PTSD
Written exposure therapy (WET) for post-traumatic stress disorder (PTSD) was just as effective as prolonged exposure therapy (PE), results of a new randomized clinical trial show. Investigators also found that participants randomly assigned to receive WET were significantly less likely…
Read MoreCaitlin Is Changing the Lives of Some of Our Tiniest, Most Vulnerable Animals
https://www.youtube.com/embed//3oG7USv77MA Caitlin M. wasn’t a cat person, but when she met her husband, a described “big cat guy,” she quickly fell in love with felines. Living in England at the time, Caitlin and her husband knew they wanted a cat,…
Read MoreReducing viral infection risks when sending kids off to school
It’s back to school for many kids around the nation. And once they hit the classroom, you may notice more runny noses and other symptoms associated with viral and bacterial infections. Dr. Nipunie Rajapakse, a pediatric infectious diseases physician with…
Read MoreEngineered adeno-associated virus vector yields high transduction of the brain vasculature
Reviewers’ Notes Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells. The study describing the characterization of this novel AAV capsid is published in the peer-reviewed journal Human…
Read MoreA new pathway to regenerate myelin discovered
A study led by Dr. Hyun Kyoung Lee, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, has discovered a new biological mechanism to regenerate and repair…
Read MorePioneering drug for rare kidney disease improves outcome for patients
Reviewers’ Notes A pioneering drug for a rare kidney disease prevents organ failure and significantly improves the outcome for patients, new research has confirmed. Atypical Haemolytic Uraemic Syndrome (aHUS) is a genetic life-threatening condition caused by a defect in the…
Read MoreGene editing system restores dystrophin function in stem cells from patients with Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a muscle degeneration disorder caused by mutations affecting the dystrophin gene. On August 24 in the journal Stem Cell Reports, researchers show how a dual CRISPR RNA method restored dystrophin protein function in induced pluripotent…
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